Ion Channels in Sperm Physiology and Male Fertility and Infertility

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Ion channels in sperm physiology.

Fertilization is a matter of life or death. In animals of sexual reproduction, the appropriate communication between mature and competent male and female gametes determines the generation of a new individual. Ion channels are key elements in the dialogue between sperm, its environment, and the egg. Components from the outer layer of the egg induce ion permeability changes in sperm that regulate...

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Male fertility and infertility

in 30–50% of sub-fertile couples the male partner has poor semen quality, either because of low sperm count, poorly motile sperm or sperm with abnormal size and shape (morphology). This may result from inherent genetic factors, poor pre-natal testicular development or adult exposure to gonadotoxic agents. There are few proven therapies to improve semen quality. Therefore, the number and quality...

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Sperm counts and sperm sex ratio in male infertility patients.

In recent years, investigators have noted a trend toward a declining proportion of male births in many industrialized nations. While men bear the sex-determining chromosome, the role of the female partner as it pertains to fertilization or miscarriage may also alter the gender ratio. We attempted to determine a man's secondary sex ratio (F1 generation) by directly examining the sex chromosomes ...

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Male infertility, female fertility and extrapair copulations.

Females that are socially bonded to a single male, either in a social monogamy or in a social polygyny, are often sexually polyandrous. Extrapair copulations (EPC) have often been suggested or rejected, on both empirical and theoretical grounds, as an important mechanism that enables females to avoid fertility risks in case their socially bonded male is infertile. Here, we explore this possibil...

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Imprisonment-associated sperm clumping and male infertility.

OBJECTIVE This observational, retrospective study investigated infertility among Iraqi men who had been long-term prisoners of war. METHODS Routine seminal fluid analyses were undertaken in former prisoners with suspected infertility attending the Ramadi Infertility Clinic, Ramadi, Iraq; semen samples were also microscopically evaluated in these patients. RESULTS In 16 out of 38 patients (...

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ژورنال

عنوان ژورنال: Journal of Andrology

سال: 2012

ISSN: 0196-3635

DOI: 10.2164/jandrol.111.015552